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KMID : 0338420200350061411
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Korean Journal of Internal Medicine
2020 Volume.35 No. 6 p.1411 ~ p.1423
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A population-based observational study of patients with pulmonary disorders in intensive care unit
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Lee Hyun-Woo
Ji Eun-Jeong
Ahn So-Yeon
Yang Hye-Joo
Yoon Seo-Young
Park Tae-Yeon
Lee Yeon-Joo
Lee Jin-Woo
Lee Sang-Min
Choi Seung-Hye
Cho Young-Jae
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Abstract
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Background/Aims: Only a few epidemiologic studies on the patients with pulmonary disorders admitted to intensive care unit exist. We investigated the characteristics and clinical outcomes of the patients with severe pulmonary disorders.
Methods: The sample cohort database of National Health Insurance Sharing Service from 2006 to 2015 was used. Operational definition of critically ill patients was adults who were either admitted to intensive care unit for at least 3 days or expired within first 2 days in the unit. The pulmonary disorder group comprised of critically ill patients with respiratory disease as the main diagnosis.
Results: Among the 997,173 patients, 12,983 (1.3%) in 383 intensive care units were categorized as critically ill. Patients in the pulmonary disorder group tended to have more comorbidities or disabilities. The length of hospital stay and duration of mechanical ventilation were longer in the pulmonary disorder group. Overall mortality and re-admission were higher in the pulmonary disorder group, with adjusted incidence rate ratios of 1.22 (95% confidence interval, 1.18 to 1.27) and 1.26 (95% confidence interval, 1.17 to 1.36), respectively. After adjustment by Cox regression, the pulmonary disorder group was an independent risk factor for in-hospital mortality.
Conclusions: In critically ill patients with pulmonary disorder, the use of healthcare resources was higher, and their clinical outcomes were significantly worse than the non-pulmonary disorder group.
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KEYWORD
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Critical illness, Lung diseases, Intensive care units, Patient readmission, Mortality
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